關於「trna inhibits protein synthesis」標籤，搜尋引擎有相關的訊息討論：

tRNAs as Antibiotic Targets - NCBI。

This essential and ubiquitous nature of tRNAs in protein synthesis make them prime targets for antibiotics with a vast array of natural and synthetic inhibitors ...： tw | tw。

Discovery and Analysis of Natural-Product Compounds Inhibiting ...。

We have developed a poly(U) mRNA-directed aminoacylation/translation (A/T) protein synthesis system composed of phenylalanyl-tRNA synthetases (PheRS), ribosomes ...： tw | tw。

Discovery of Novel Oral Protein Synthesis Inhibitors of ...。

2016年9月23日 · tuberculosis in TB mouse infection models. We applied the oxaborole tRNA-trapping (OBORT) mechanism, which was first developed to target fungal ...。

Progress and challenges in aminoacyl-tRNA synthetase-based ...。

In addition to their canonical role in protein synthesis, ARSs are also ... useful ARS inhibitors are emerging to manage microbial and parasite infections.。

Identifying the targets of aminoacyl-tRNA synthetase inhibitors by ...。

2013年6月12日 · Abstract. Aminoacyl-transfer RNA (tRNA) synthetases (RS) are essential components of the cellular translation machinery and can be exploited ...。

Nascent peptides that block protein synthesis in bacteria | PNAS。

2013年3月5日 · In other stalling motifs, peptidyl transfer to certain aminoacyl-tRNAs is inhibited. In particular, three consecutive Pro codons pose a ...。

Inhibition of Protein Synthesis by Antibiotics - Sigma-Aldrich。

Tetracyclines, including doxycycline, prevent the binding of aminoacyl-tRNA by blocking the A (aminoacyl) site of the 30S ribosome. They are capable of ...： 。

The protein translation machinery is expressed for maximal ... - Nature。

2020年10月16日 · Here, we show that the growth rate-dependence of the concentrations of ribosomes, tRNAs, mRNA, and elongation factors observed in Escherichia ...。

Aminoacyl-tRNA synthetase dependent angiogenesis revealed by a ...。

2015年8月14日 · The ability of threonine to rescue the inhibition of translation by both compounds was compared in a cell free protein synthesis assay and this ...。

Non-AUG translation: a new start for protein synthesis in eukaryotes。

For example, it is now clear that the inclusion of translation inhibitors (such as ... If a non-AUG start codon is used for initiation, what aminoacyl-tRNA ...